Fusion Prostate Biopsy

Fusion biopsy is a diagnostic procedure that takes targeted samples in areas suspicious for prostate cancer.

Prostate cancer is the most common malignant tumor in men. Fortunately, it has a high cure rate if diagnosed early and treated appropriately.

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What is Fusion Prostate Biopsy?

The diagnosis of prostate cancer has traditionally been based on the determination of the PSA value in blood and the performance of a digital rectal examination. When the PSA was elevated or an abnormal digital rectal examination was detected, a blind biopsy with ultrasound was performed. Currently, there are more advanced diagnostic methods to assess whether a man has prostate cancer and to determine its severity. This is the case of fusion biopsy, which takes the image from magnetic resonance imaging, which for the first time offers images of solid prostate tumors, and fuses it with an ultrasound scanner to perform targeted biopsies.

Fusion biopsy, the evolution of diagnostic tests

When there is a clinical situation of suspected prostate cancer, a multiparametric magnetic resonance imaging (mpMRI) of the prostate is performed. This is a high-resolution imaging test that will play an important role in performing the biopsy since, by fusing this information with the real-time ultrasound image, it allows samples to be taken from the suspicious areas and the state of the prostate to be analyzed in detail.

For the first time it is possible to see the tumor inside the prostate gland, which allows not only to know its local situation (size, location, capsular involvement or periprostatic structures), but also to direct the taking of biopsies to these lesions.

But we can still go a step further in performing fusion biopsies thanks to PET-PSMA (positron emission tomography). While prostate mpMRI helps in the static anatomical identification of suspicious areas of malignancy, PET-MRI-PSMA makes it possible to see dynamic areas of tumor activity. Previously invisible tumors can be diagnosed, even with PSA less than 1.

fusion-biopsy

Of all the diagnostic tools available, this is the one that yields the most definitive information and allows greater precision in taking samples that will later be analyzed by a specialized pathologist.

Obtaining all these details will allow us to plan a focal therapy for prostate cancer, that is, to treat exclusively the area affected by the tumor plus a safety margin, being a less invasive treatment. For this purpose, we have the Hugo and Da Vinci robotic systems, which translate the surgeon's movements, improving ergonomics and reducing tremor. In addition, it allows a real three-dimensional vision of the operative field with a high image quality that guarantees clarity and precision of the details.

 How is fusion biopsy performed?

Fusion biopsy is performed in the operating room. After a short sedation, the puncture needle is introduced through the perineal area for greater precision and lower infection rate. Once the sample is removed, it is sent to the pathologist.

The test lasts about half an hour. Two hours after the procedure, the patient can go home. It is normal to feel a slight discomfort in the perineum during the first hours, which can be alleviated with local cold and anti-inflammatory drugs.

Advantages of Fusion Prostate Biopsy
  • Accurate detection and analysis.
  • Safer.
  • Fewer complications: infection, rectoragia and others.
  • It largely avoids false negatives and retesting.
  • It allows planning a focal therapy.
Disadvantages of Fusion Prostate Biopsy
  • More expensive.
  • Requires operating room.
  • It must be performed by a highly skilled team.
Prostate biopsy by image fusion, as reflected in the European Association of Urology Guidelines and other consensus documents, is the best diagnostic strategy. This advance also allows us to take a giant step forward in the treatment of prostate cancer.
Our experience with Fusion Prostate Biopsy

Fusion biopsy requires a highly specialized team with a high level of experience, as well as the latest technology. For this reason, we use the KOELIS device to carry out this diagnostic test.

At ROC Clinic we have performed more than 400 fusion biopsies, including in patients with a PSA lower than 1. Also, committed to the training of other professionals, we are teachers in the program of prostate biopsy by fusion "FusionROC", carried out at the University Hospital HM Sanchinarro.

+400

In patients with a PSA of less than 1

Teachers in the fusion prostate biopsy program -FusionROC- in HM Sanchinarro

News
of ROC Clinic in Fusion Prostate Biopsy

Research

Initial experience with thulium fiber laser for prostate enucleation: Analysis of the intraoperative and short-term outcomes in a prospective, multicenter cohort.

They ask us
in the Consultation

What complications can occur in a prostate fusion biopsy?

A fusion biopsy is a very safe and accurate test and usually has fewer complications such as infection or rectoragia.

I have had several prostate biopsies and all have been negative but my PSA keeps going up, could fusion biopsy be the definitive test to rule out cancer?

If, despite negative repeat prostate biopsies, there is still clinical suspicion of prostate cancer, multiparametric magnetic resonance imaging will provide information on the existence or not of a tumor and will allow us to take tissue from the affected area.

If prostate cancer does not produce symptoms, when should I have such a diagnostic test?

From the age of 40 onwards, all men should have a prostate check-up since it is very common to suffer from prostate problems from that age onwards. If during these check-ups, there is any suspicion of prostate cancer, we will proceed to more exhaustive tests.

How should I prepare before having a fusion biopsy?

Tell your doctor about any medications you take and your allergies. You may have to stop taking anticoagulants during the previous days and take some antibiotics before the test. It is advisable to eat a light meal before the test. You should also remove any metal objects you are carrying and report any previous surgeries or metal implants such as pacemakers, aneurysm clips, or joint replacements.

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Team
of the Fusion Prostate Biopsy Unit

Dr. Javier Romero-Otero

Dr. Javier Romero-Otero

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Dr. Juan Justo Quintas

Dr. Juan Justo Quintas

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Dr. Esther García Rojo

Dr. Esther García Rojo

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Dr. Gino Marcelo Espinales Castro

Dr. Gino Marcelo Espinales Castro

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Dr. Silvia García Barreras

Dr. Silvia García Barreras

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Dr. Elena Peña

Dr. Elena Peña

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